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Research areas

The Research unit of Cardiac, Thoracic, and Vascular surgery at the University of Southern Denmark (SDU) and Odense University Hospital (OUH) excels in clinical, health economic, translational, and experimental research.

The unit serves as the headquarters for the Cardiovascular Centre of Excellence (CAVAC) and is part of the Elite Centre for Individualised Treatment of Arterial Disease (CIMA), as well as the Odense Artery Biobank. In addition, we collaborate with several departments and institutes under SDU and OUH, as well as regional, national, and international partners.

The unit has affiliated professors, adjunct professors, research directors, postdocs, PhD and research year students, as well as technical and administrative staff.

Researchers interested in collaboration are always welcome to contact our research unit for participation in projects or the development of their own projects.

Publications

Here you will find an overview of our publications

 

Research projects

PLUS - Projekt LUngekræftScreening i Syddanmark

PREPARE - Personalized Risk Estimation and Prevention of Cardiovascular Disease

TeleGraft

Other projects and studies

The ATLAAC study is a randomized trial aimed at determining the necessity of anticoagulant therapy for patients with atrial fibrillation following surgical closure of the left atrial appendage.

 

Contact

 Kristina Gosvig - kristina.gosvig@rsyd.dk

Lars Riber - lars.riber@rsyd.dk.

Odense Artery Biobank, established in collaboration with the Centre for Individualised Medicine in Arterial Diseases (CIMA), routinely collects blood and tissue samples during carotid and femoral endarterectomies, aortic aneurysm surgeries, as well as project-specific samples from the heart, lungs, surrounding fat, and other tissues. This initiative aims to investigate the roles of various genes, lipids, and proteins in cardiovascular diseases.

Website: Odense Artery Biobank

 

Contact

Heart and Heart Valves: Lars Riber - lars.riber@rsyd.dk

Aorta and Peripheral Arteries: Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk

 

Randomized Screening Study for Cardiovascular Disease

A randomized screening study involving 78,000 men aged 60-74. The invited participants underwent CT scans of the major arteries from the neck to the legs to detect coronary calcification and aneurysms. Blood pressure measurements were taken on the arms and ankles to identify peripheral arterial disease, heart rhythm was assessed, and cholesterol and blood sugar levels were measured.

There are excellent opportunities for a research year.

Website: The Danish Cardiovascular Screening

 

Contact:

Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk

DanVasc is a national research project involving all vascular surgery departments in Denmark, aimed at improving the treatment of vascular diseases. The project's first step is the DanVasc Survey, a questionnaire study involving 6,000 patients nationwide, designed to gather valuable insights into vascular disease.

There are excellent opportunities for a research year.

Website: DanVasc 

 

 

Contact:

Marie Dahl - marie.dahl@midt.rm.dk

Britt Borregaard - britt.borregaard@rsyd.dk

Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk

A regionally supported research program dedicated to developing a medical treatment for abdominal aortic aneurysms. This program utilizes systematic reviews, microsurgery-based animal models, pharmaco-epidemiological studies, and clinical trials in collaboration with the Odense Artery Biobank.

Excellent opportunities for research years, potentially leading to a PhD.

 

Contact:

General Inquiries: Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk

Pharmacoepidemiology: Joachim Sjer S. Kristensen - joachim.sjer.s.kristensen@rsyd.dk

Animal Experimental Studies: Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk and Jens Stubbe - jstubbe@health.sdu.dk

A regional case-control study utilizing artificial intelligence, CT post-processing, finite element analysis, and other advanced techniques to develop a more personalized risk estimation for aortic rupture and dissection. This approach aims to improve upon the current diameter-based criteria for preventive surgery.

 

Contact:

Mads Liisberg - mads.liisberg@rsyd.dk

Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk

The LIMIT study is a randomized trial in collaboration with several international centres, designed to evaluate the necessity of anticoagulant therapy for patients who have undergone surgery with a mechanical aortic valve prosthesis.

 

Contact:

Lars Riber - lars.riber@rsyd.dk

Mechanical Circulatory Support for Cardiac Patients

A comprehensive collaboration between cardiologists, anesthesiologists, and cardiac surgeons to provide mechanical circulatory support for cardiac patients.

 

Contact:

Lars Riber - lars.riber@rsyd.dk

Mechanical Circulatory Support for Cardiac Patients

A comprehensive collaboration between cardiologists, anesthesiologists, and cardiac surgeons to provide mechanical circulatory support for cardiac patients.

 

Contact:

Lars Riber - lars.riber@rsyd.dk

The SALVAGE study is a clinical trial aimed at investigating the genetic modalities associated with aortic stenosis and the structural impacts this condition has on the heart. This is achieved through the use of whole-genome studies and cardiac MR, CT, and ultrasound imaging.

 

Contact:

  Lisa Gundestrup - lisa.gundestrup@rsyd.dk

Lars Riber - lars.riber@rsyd.dk

The STARC study is a double-blind, randomized controlled trial aimed at evaluating the effect of statins on the incidence of postoperative atrial fibrillation following surgical aortic valve replacement.

 

Contact:

  Lytfi Krasniqi - lytfi.krasniqi@rsyd.dk

Lars Riber - lars.riber@rsyd.dk

The Stembrace Study

The Stembrace study explores the potential of stem cell involvement in the treatment of various conditions, including heart diseases. We serve as the cardiac surgical arm of OUH's frontline centre.

 

Contact:

Lars Riber - lars.riber@rsyd.dk

The SUNDAY Trial is a randomized, open-label, observer-blinded, two-arm controlled study investigating whether thoracic endovascular aortic repair (TEVAR) affects five-year survival rates among patients with uncomplicated Stanford type-B aortic dissection.

Website: SUNDAY Trial

 

Contact:

Maria Lyck Hansen - maria.lyck.hansen@rsyd.dk

A cross-sectoral and multidisciplinary project, Viborg Municipality has been offering a health examination, known as the Viborg Screening Program (VISP), to all 67-year-old residents since 2014. The aim is to detect cardiovascular diseases and diabetes early and subsequently provide preventive measures. Hospitalsenhed Midt and Department T at OUH have been involved in developing this initiative and are behind numerous research projects related to the screening.

There are excellent opportunities for master's theses and research years.

Website: VISP 

 

Contact:

Marie Dahl - marie.dahl@midt.rm.dk

Jes Sanddal Lindholt - jes.sanddal.lindholt@rsyd.dk


Last Updated 01.08.2024