Contact Person
Lars Melholt Rasmussen, Professor, Consultant, DMSc
lars.melholt.rasmussen@rsyd.dk; https://portal.findresearcher.sdu.dk/en/persons/lmrasmussen
Research aim
We aim at discovering, validating and implementing biochemical markers for risk stratification diagnosis,and monitoring of cardiovascular diseases.
Project examples
- The development and validation of blood-based and other screening tools for cardiovascular diseases using a large screening cohorte (DANCAVAS and PREPARE)
- Markers for phosphate metabolism and their association with cardiovascular diseases
Available cohorts and infrastructures
DANCAVAS (ref – trial + baseline) PUBMED #26637993 & 30919411
Collaborators
- Axel Diederichsen, Professor, Cardiology, Dept. B, OUH
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Jes Lindholt, Professor, Vascular Surgery, Dept. T, OUH
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Mette Sørensen, Ass. Professor, Epidemiology, SDU
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Per Eriksson, Cardiovascular Medicine, Karolinska Institute, Stockholm, Sweden
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Maria Sabater-Lleal, PhD, Sant Pau Biomedical Researche Institute, Barcelona, Spain
Funding
- Part of CIMA, a research center at OUH/SDU (grant total 28 mil), 2013-2022
- Work package under PREPARE study (grant total 20 mill DKK from Innovation Fund Denmark)
- Danish Cardiovascular Academy (DCA) & Danish Heart Association, PhD grant (Nicolai Bjødstrup Palstrøm ), 2022-2025
Publication examples
- Does diabetes modify the effect of heparin on plasma proteins? - A proteomic search for plasma protein biomarkers for diabetes-related endothelial dysfunction. Soerensen M, Debrabant B, Halekoh U, Møller JE, Hassager C, Frydland M, Hjelmborg J, Beck HC, Rasmussen LM.
- J Diabetes Complications. 2021 Jun;35(6):107906
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STEMI, Cardiogenic Shock, and Mortality in Patients Admitted for Acute Angiography: Associations and Predictions from Plasma Proteome Data.
Plasma CCN2 is independently related to subsequent need for abdominal aorta aneurysm repair.
Debrabant B, Halekoh U, Soerensen M, Møller JE, Hassager C, Frydland M, Palstrøm N, Hjelmborg J, Beck HC, Rasmussen LM.
Shock. 2021 Jan 1;55(1):41-47
Larsen JH, Rasmussen LM, Lindholt JS, Steffensen LB
Growth Factors. 2019 Aug;37(3-4):146-152
- CT-Detected Growth of Coronary Artery Calcification in Asymptomatic Middle-Aged Subjects and Association With 15 Biomarkers.
Diederichsen SZ, Grønhøj MH, Mickley H, Gerke O, Steffensen FH, Lambrechtsen J, Rønnow Sand NP, Rasmussen LM, Olsen MH, Diederichsen A. JACC Cardiovasc Imaging. 2017 Aug;10(8):858-866