Jakub Sedzinski

The research focus of the laboratory of Assoc. Professor Jakub Sedzinski at UCPH is to investigate the fundamental principles governing the development and regeneration of mucociliary epithelium (MCE). Specifically, they aim to elucidate the mechanical and molecular processes driving MCE differentiation and renewal from stem cells, with the ultimate aim of contributing to novel therapeutic approaches for respiratory diseases linked to impaired MCE.

To this aim, the group uses interdisciplinary methods, combining cell and developmental biology, physics and computation applied to developing frog embryos and human-derived respiratory organoids.