Proteomics
We study proteins, oligonucleotides, lipids and carbohydrates by MALDI and ESI mass spectrometry. We also use a variety of chemical, biochemical and bioinformatics techniques.
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Functional Genomics
In the Functional Genomics & Metabolism Research Unit, we use advanced genomic tools to understand the transcriptional plasticity and regulatory networks involved in differentiation, metabolism and disease of mammalian cells.
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Center of Excellence
Clinical Genomics
Focus of the research lies in clinical genomics, transcriptomics and epigenomics. Computational methods are developed for making the massive next-generation sequencing (NGS) data emerging nowadays usable in clinical practice. Another research focus is on genetics and genomics of human aging and aging-related diseases using biostatistics and bioinformatics approaches applied to genomics, transcriptomics, epigenomics and proteomics data.
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Metabolomics / Lipidomics
The major theme of our research revolves around how metabolism and signalling are coordinated to meet the nutritional needs of cells and organism with emphasis on how lipids are synthesized, transported and metabolized and how they act as signalling molecules.
We aim at understanding the relationship between lipid metabolism and lipid mediated signalling in the development of various diseases like obesity, diabetes, neurological disorders and cancers.
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Bioimaging
The research is focused on the use of advanced Bioimaging techniques to answer fundamental questions in biological systems. With the techniques we develop, we can extract more information than was previously available from simple images.
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Epidemiology
We study human development and aging and the link between them, using data from large Danish population-based surveys. The Danish health registers and The Danish Twin Registry are valuable resources in the study of gene-environment interactions in human development and aging.
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